Osteogenic Fuction of Periosteum and Periosteal Cells of Rabbit

INTRODUCTION The periosteum may have an important function of new bone formation because of the abundant blood supply and the presence of osteoprogenitor cells. Periosteal cells have also been used for bone and cartilage formation. Though there have been many studies about the osteogenesis using periosteum, and osteogenic activity of osteoprogenitor cells such as mesenchymal stem cells(MSCs), little study has focused on the expression of osteogenic markers and the amount of osteocalcin from the cultured periosteal cells. Also, in authors’ knowledge, there has not been comparative research between periosteum transplant and periosteal cells-scaffold composite transplant in terms of osteogenic capacity. In this study, the osteogenic function of periosteal cells were evaluated by expression of osteogenic markers, and the difference of osteogenic capacity between periosteum and periosteal cells scaffold composite was studied by doing in vivo transplantation.